Publications

Recent select publications:

1. Latini S.*, Venafra V.*, Massacci G., Bica V., Graziosi S., Pugliese G.M., Iannuccelli M., Frioni F., Minnella J., Marra J.D., Chiusolo P., Pepe G., Helmer-Citterich M., Mougiakakos D., Boettcher M., Fischer T., Perfetto L.* and Sacco F.*. Unveiling the signaling network of FLT3-ITD AML improves drug sensitivity prediction eLife, 2024 https://elifesciences.org/reviewed-preprints/90532/figures

2. Massacci G., Perfetto L., Sacco F.*. The Cyclin-dependent kinase 1: more than a cell cycle regulator. British Journal of Cancer, 2023 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10667339/

3. Pugliese G.M.*,  Venafra V.*, Bica V.*, Massacci G., Latini S., Graziosi S., Fischer T., Mougiakakos D., Boettcher M., Perfetto L., Sacco F. Impact of FLT3-ITD location on cytarabine sensitivity in AML: a network-based approach Leukemia Letter, 2023 https://www.nature.com/articles/s41375-023-01881-5

4. Massacci G.*, Venafra V.*, Latini S., Bica V., Pugliese G.M., Graziosi S., Klingelhuber F., Krahmer N., Fischer T., Mougiakakos D., Boettcher M., Perfetto L.*and Sacco F.* A key role of the WEE1-CDK1 axis in mediating TKI-therapy resistance in FLT3-ITD positive acute myeloid leukemia patients Leukemia, 2022 https://www.nature.com/articles/s41375-022-01785-w

5. Caliskan ÖS, Massacci G, Krahmer N, Sacco F.  Phosphoproteomics and Organelle Proteomics in Pancreatic Islets. Methods in Molecular Biology, 2022

6. Pugliese GM, Latini S, Massacci G, Perfetto L, Sacco F.  Combining Mass Spectrometry-Based Phosphoproteomics with a Network-Based Approach to Reveal FLT3-Dependent Mechanisms of Chemoresistance. Proteomes, 2021

7. Reggio A, Rosina M, Krahmer N, Palma A, Petrilli LL, Maiolatesi G, Massacci G, Salvatori I, Valle C, Testa S, Gargioli C, Fuoco C, Castagnoli L, Cesareni G, Sacco F.  Metabolic reprogramming of fibro/adipogenic progenitors facilitates muscle regeneration. Life Science Alliance 2020

8. Sacco F, Seelig A, Humphrey SJ, Krahmer N, Volta F, Reggio A, Marchetti P, Gerdes J, Mann M.  Phosphoproteomics Reveals the GSK3-PDX1 Axis as a Key Pathogenic Signaling Node in Diabetic Islets. Cell Metabolism, 2019

9. Sacco F, Perfetto L, Cesareni G.  Combining Phosphoproteomics Datasets and Literature Information to Reveal the Functional Connections in a Cell Phosphorylation Network. Proteomics, 2018

10. Palma A, Iannuccelli M, Rozzo I, Licata L, Perfetto L, Massacci G, Castagnoli L, Cesareni G, Sacco F., Integrating Patient-Specific Information into Logic Models of Complex Diseases: Application to Acute Myeloid Leukemia. Journ. of Persalised Medicine, 2021